ea0077p192 | Metabolism, Obesity and Diabetes | SFEBES2021
Iqbal Zohaib
, Fachim Helene
, Gibson John
, Baricevic-Jones Ivona
, Campbell Amy
, Geary Bethany
, Donn Rachelle
, Syed Akheel
, Wetton Anthony
, Soran Handrean
, Heald Adrian
Aims: We used sequential window acquisition of all theoretical fragment ion spectra Mass Spectrometry (SWATH-MS) to identify proteins acting as markers of remission of type 2 diabetes (T2DM) in patients who lost weight after bariatric surgery.Background: Bariatric surgery results in remission of T2DM in up to 80% of patients. The mechanisms underpinning are largely unknown. N-acetylmuramoyl-L-alanine amidase (PGLRYP2) is an immune response enzyme that br...